Last Updated on April 22, 2025
Dog owners know that pet accidents can happen at any time, and cleaning up dog pee from a mattress is a task no one looks forward to. With the right approach, removing urine stains and getting rid of odors is easier than it seems. The most effective way to clean dog pee out of a mattress is to blot the area, use a vinegar-based cleaning solution, sprinkle on baking soda, and vacuum when dry learn more about these steps.
Quick action is important. Acting soon after the accident helps prevent long-term smells and stains. This guide covers what supplies to keep on hand, the best cleaning steps, and extra tips for keeping the mattress fresh after any pet mess.
Key Takeaways
- Quick response stops stains and odors from setting in.
- Use household supplies like vinegar and baking soda for best results.
- Good cleaning habits help prevent future dog pee accidents.
Immediate Steps to Take After Your Dog Pees on the Mattress
Acting fast is important when cleaning pet urine from a mattress. Addressing the stain and odor as soon as possible can help prevent long-term damage and stop bacteria from growing.
React Quickly
The sooner you start cleaning, the easier it is to remove the urine stain and smell. Fresh pet pee is much simpler to handle compared to pee that has dried.
As soon as you find a wet spot, strip off all bedding and place it in the wash right away. This stops urine from soaking deeper into the fabric and foam. Air out the area by opening windows or turning on a fan to help control odors and start the drying process.
Quick action helps prevent bacteria and mold growth. It also makes it less likely for the dog to return to the same spot in the future.
Blotting Up Excess Urine
Use clean, absorbent paper towels or a dry cloth to blot the area. Press down gently to soak up as much liquid as possible without spreading the stain. Avoid rubbing, as this can push the urine deeper into the mattress and cause a lingering smell.
Continue to blot and replace the paper towels until they come away dry. For larger messes, a stack of paper towels can absorb more moisture.
If needed, use a wet/dry vacuum on the damp part of the mattress for extra suction. Getting out as much urine as possible makes later cleaning steps more effective. Never scrub or use excessive force, as this can spread the dog pee or damage the fabric.
Preparing the Area for Cleaning
Clear away any bedding, blankets, or stuffed toys near the stained spot so the mattress is exposed. This makes it easier to treat just the affected spot and keeps clean items from getting dirty.
Check if the area is still wet. If it is, continue blotting with fresh paper towels. Once it is mostly dry, use a spray bottle with cool water to lightly mist around the urine spot. This helps stop the urine from drying out and locking in odor.
Plan to use a cleaner made for pet urine, or a vinegar solution, right after the area is ready. Using the right products is key to fully removing dog pee and odors. For more step-by-step instructions and suggestions on supplies, visit this detailed guide on cleaning pet urine from a mattress.
Essential Supplies and Materials
Cleaning a mattress after a dog accident is easier with the right products and tools. Simple household items like baking soda, vinegar, and a spray bottle work well, but special cleaners may help with strong smells.
Choosing the Right Cleaning Products
An enzyme cleaner is best for removing pet urine smells. These cleaners break down the proteins in urine, which helps get rid of lingering odor. For lighter stains or early treatment, a mix of white vinegar and water can be effective. Vinegar helps neutralize ammonia and breaks up residue.
Baking soda is useful for absorbing moisture and smells. Sprinkle it over the stained area after cleaning and let it sit before vacuuming. A store-bought disinfectant can be used if the mattress needs extra sanitation, but make sure it is safe for fabrics. A mild laundry detergent can also be added to cleaning solutions for extra cleaning strength.
Gathering Materials Needed to Remove Stains
A few basic supplies make the cleaning process easier. Most people need a spray bottle to mix and apply cleaning solutions evenly. Paper towels or a clean dry towel are used immediately to blot up as much liquid as possible.
A vacuum is helpful after the area has dried and baking soda has done its job. Gather all supplies before you start, so you can work quickly and avoid letting the urine set into the mattress. Optional items include gloves to protect hands and a measuring cup for mixing solutions.
These items are commonly found in most homes, so there is no need to buy special products unless preferred. For further tips, check advice that explains you can use basic supplies and common cleaners to tackle pet messes.

Effective Methods for Removing Dog Pee from a Mattress
Removing dog urine from a mattress requires cleaning and neutralizing the odor. Using ingredients like vinegar, baking soda, and enzymatic cleaners can address both stains and smells quickly.
Using Vinegar and Baking Soda Solution
A vinegar and baking soda solution can break down urine stains and neutralize odor. First, blot up as much liquid as possible using a clean towel or paper towel. Avoid rubbing, as this can spread the stain further into the mattress.
Mix one part white vinegar and one part water in a spray bottle. Spray the affected area until damp but not soaked. Let it sit for 10-15 minutes to help dissolve the stain and start scent removal.
After blotting up the vinegar solution, sprinkle a thick layer of baking soda over the damp area. Allow the baking soda to sit for several hours or overnight. It helps draw out remaining moisture and absorbs odors. Finally, vacuum up the baking soda. For step-by-step details, see The best ways to remove urine stains and smells from your mattress.
Enzymatic Cleaners for Pet Urine Stains
Enzymatic cleaners are designed to remove pet stains by breaking down the proteins in urine. This method is often more effective than homemade solutions for tough odors and set-in stains.
Look for a pet-specific enzyme cleaner at most pet stores or online. Read and follow the product label. Usually, the urine stain should be saturated with the enzyme solution and left to sit for 10–20 minutes to give the enzymes time to work.
After the wait, blot up excess moisture with a clean cloth. Allow the mattress to air dry fully before making the bed. Enzyme cleaners can help remove both the stain and unpleasant odors. For more information, see why enzyme cleaners are recommended for pet messes.
Try Hydrogen Peroxide and Soap
Hydrogen peroxide mixed with mild soap can help lift stubborn urine stains and disinfect the spot. Use 3% hydrogen peroxide, which is commonly found in pharmacies.
Mix about one cup of hydrogen peroxide, one tablespoon of mild dish soap, and one tablespoon of baking soda. Stir gently to avoid foam, then apply the mixture directly onto the stained area using a spray bottle or by dabbing with a cloth.
Let the solution sit for up to 15 minutes. Blot it dry with a clean towel, then sprinkle a fresh layer of baking soda over the area to soak up remaining moisture and help with odor. After a few hours, vacuum up the dry baking soda. This homemade stain remover works well for both recent and old urine stains, and it also helps whiten fabric.
Deep Cleaning and Sanitizing the Mattress
Deep cleaning is needed to remove smells, harmful germs, and prevent repeat accidents.
Vacuuming and Air Drying
Let the affected area dry as much as possible. Use paper towels or a clean cloth to blot urine, pressing gently to avoid spreading it further. Don’t rub or scrub, as this can push urine deeper into the mattress layers.
Once the spot is mostly dry, use a vacuum cleaner with an upholstery attachment to pick up baking soda, dried residue, and pet hair. Vacuuming also helps pull up any leftover urine crystals, which can cause lingering smells and stains. Move slowly so the vacuum can lift dirt and particles from the surface and deeper layers.
Let the mattress sit in a well-ventilated space or near a fan to finish drying. Fresh air and sunlight can help dry the fabric faster and reduce odors. If possible, prop the mattress upright to let air flow all around it.
Sanitizing with Disinfectant
After drying, it’s important to sanitize the area to remove germs and bacteria from the urine. Use a disinfectant spray or wipe labeled as safe for fabrics. Lightly mist or wipe the spot—avoid soaking the mattress, since too much moisture can lead to mold or mildew.
Let the disinfectant sit for the recommended time listed on the label to make sure it kills most germs. Using a clean, damp cloth, gently blot up any excess product. Many people use household products like hydrogen peroxide as a disinfectant, but always test on a small spot first as it may bleach some fabrics.
Repeat the sanitizing step on large or older stains for added safety. Stronger products like enzyme cleaners are effective for pet stains and work by breaking down proteins in the urine that attract bacteria.
Neutralizing Odors and Urine Smell
Odor removal is just as important as cleaning. Sprinkle a thick layer of baking soda over the affected area. Baking soda helps absorb both moisture and smells. Let it sit for at least several hours, or overnight for tough pet odors.
After the sitting period, vacuum all the baking soda off the mattress carefully. For a deeper clean, spray a mixture of white vinegar and water onto the spot before adding baking soda. This creates a natural reaction that helps neutralize urine smell and deodorize the fabric. Some households use a pet odor eliminator or specialized deodorizing products made for mattresses for added freshness.
Repeat the baking soda and vacuum steps if you still notice any smell. Using a dedicated pet odor neutralizer can also help prevent pets from marking the same spot again.
Alternative and Natural Solutions
Natural methods for cleaning dog urine from a mattress can be effective and gentle. Common household items like lemon juice, water, and citrus oils neutralize odors while helping avoid harsh chemicals and strong fumes.
Lemon Juice and Water Mixture
A mixture of lemon juice and water is a popular natural cleaning solution. Lemons contain citric acid, which helps break down urine stains and neutralize odors. To make a cleaner, mix equal parts fresh lemon juice with warm water in a spray bottle.
Spray the stained area lightly. Gently blot with a clean cloth to absorb moisture and lift the stain. The natural acids in lemon juice leave a mild, fresh scent. For larger stains, repeat the process once dry. Some people add a pinch of baking soda for extra cleaning power.
Using lemon juice and water is safe for most mattresses and does not leave harsh residues. This method works well for recent stains but may need several applications for older odors. Lemon solutions also help remove bacteria and leave mattresses smelling clean.
Avoid Harmful Chemicals
Many cleaning products have strong chemicals that can damage a mattress or irritate sensitive skin. Using natural alternatives reduces exposure to ingredients like bleach and ammonia.
When cleaning a mattress, avoid sprays with alcohol, chlorine, or synthetic fragrances. These chemicals can linger in the fabric, cause allergic reactions, and shorten your mattress’ lifespan. Instead, use DIY options like vinegar, baking soda, or lemon juice and water, which are safer for households with pets, children, or sensitive skin.
Choose fragrance-free and dye-free products when possible. Reading labels and looking for plant-based ingredients helps protect indoor air quality and your mattress. By choosing natural cleaning solutions, you minimize risks while still removing urine smells and stains.
Using Citrus Essential Oil
Citrus essential oil, like lemon or orange oil, adds a pleasant scent and has natural antibacterial properties. To use, add a few drops of citrus essential oil to a spray bottle filled with water. Shake well and lightly mist the stain after cleaning.
Benefits of using citrus essential oil include:
- Neutralizes strong odors
- Leaves a mild, refreshing fragrance
- May help break down bacteria
Allow the mattress to air dry with the windows open if possible. Do not add too much oil, as it can make the mattress feel greasy. For extra cleaning strength, citrus essential oil can be mixed with baking soda before vacuuming. More details on using citrus oil can be found at How to Clean Dog Pee from a Mattress.
Proper Care After Cleaning
It is important to dry the mattress fully and take steps to keep both the mattress and bedding clean in the future. Using protection will help prevent stains, especially with foam mattresses that can soak up liquids.
Drying and Maintaining Mattress Quality
Allowing the mattress to dry fully is important to stop mold and odors. If possible, move the mattress to a sunny spot or near an open window for better airflow. Using a fan or a hair dryer on a cool setting can help dry it faster. Avoid making the bed until the mattress is completely dry.
Moisture left inside a foam mattress can lead to a musty smell or mildew. Flip and lean the mattress upright to let air reach all sides. Pat the cleaned area with a dry towel every few hours if it still feels damp. If any odor lingers, sprinkle baking soda over the spot and vacuum it off later.
A clean, dry mattress will keep its shape and be more comfortable.
Protecting with Mattress Covers and Protectors
A mattress protector helps after cleaning. It blocks spills, sweat, and pet accidents from reaching the mattress. For homes with pets, look for a waterproof mattress cover that fits snugly and can be washed in a machine.
Replace or wash the mattress protector regularly. Mattress covers add a soft layer while protecting against dust mites and allergens. Both options offer long-term protection and can prolong the life of foam mattresses.
In homes with pets or small children, using a mattress protector is the easiest way to prevent more accidents. Investing in a high-quality protector is a simple step that saves time and keeps the bedroom smelling fresh. For more on cleaning tips and protection, visit this guide to clean pet urine from a mattress.

Preventing Future Pet Accidents
Pet parents want their dogs to avoid accidents on beds. Teaching good habits, using pet repellent sprays, and checking with a veterinarian can help keep mattresses cleaner.
Establishing Good Pet Habits
Training a dog to follow bathroom routines is one of the best ways to prevent accidents. Take the dog outside often and at the same times each day, especially after eating or waking up. Praise and give small treats whenever they go outside.
Put the dog on a consistent feeding schedule to help with regular bathroom times. If the dog is young or new to the home, try crate training, as dogs usually avoid peeing where they sleep. Clean up any accidents quickly and never punish a dog for an accident after the fact, as this can make them nervous or confused. Being calm and patient helps the dog learn better.
Using Pet Repellents
Applying pet repellent sprays can deter dogs from peeing on mattresses or other spots. Look for products made for indoor use that are safe for pets. Some sprays use natural smells like citrus or vinegar that dogs do not like. Test the spray on a small part of the mattress first to make sure it does not stain or damage the fabric.
Besides sprays, keep the bedroom door closed, or use a waterproof mattress protector for another layer of defense. To make your own pet repellent, mix equal parts water and white vinegar and lightly spray it on the mattress. Always let the area dry before letting your dog near the bed again. More on different types of sprays can be found in pet repellent tips.
Consulting a Veterinarian
If a dog keeps having accidents, even with training and repellents, it could be a health problem. Urinary tract infections, diabetes, or age-related issues can cause frequent urination. A veterinarian can do tests to find out if there is a medical condition making it hard for the dog to control their bladder.
Bring a list of what the dog eats, how often they go out, and when the accidents happen. The vet may suggest changes in food, medication, or ways to manage age-related problems. Regular checkups also help spot health issues before they get worse.
Frequently Asked Questions
There are different ways to remove dog urine and stains from a mattress, depending on if the urine is fresh or dried. Some cleaning products or household items can help remove odor without damaging the mattress.
What are the most effective methods for removing dried urine stains from a mattress?
Dried urine stains usually need a cleaner that can break down the stain and smell. Enzyme cleaners work well because they break apart the proteins in urine. White vinegar mixed with water can also help loosen and lift stains from mattress fabric.
Scrub the area gently and let it air dry. Make sure to blot, not rub, so the stain does not spread.
Can hydrogen peroxide be used to clean urine from a mattress, and how should it be applied?
Hydrogen peroxide can help remove both stains and smells from dog urine. Use a mix of hydrogen peroxide, mild dish soap, and baking soda for best results. Spray or pour the mix on the stain, let it bubble for a few minutes, then blot the area with a clean cloth.
Test hydrogen peroxide on a small hidden spot first, as it can bleach some fabrics.
What immediate steps should be taken to deal with a wet urine stain on a mattress?
Blot the wet spot right away with paper towels or a dry cloth. Press firmly to soak up as much urine as possible. Do not scrub, as this can push urine deeper into the mattress.
Next, spray the area with a mix of white vinegar and water or an enzyme cleaner. Let it sit for at least 10–15 minutes, then blot again to remove moisture. For more details, see step-by-step cleaning tips from Casper.
What are the best practices for removing the smell of dog urine from a mattress?
To remove odor, use an enzyme cleaner made for pet stains, as it targets the source of the smell. Baking soda is also good for absorbing odor—sprinkle a layer on the cleaned area, let it sit for a few hours, and then vacuum. Avoid strong perfumes that only mask the smell.
For pet-specific tips, Sleep Foundation recommends an enzyme product for deep odor removal.
How can you clean urine from a memory foam mattress without causing damage?
Memory foam should not be soaked with water or harsh chemicals since it can trap moisture inside. Use as little liquid as possible and blot up fluids quickly. Spray a light mist of cleaner, blot with a towel, and let the mattress air dry completely.
Never use hot water or put memory foam in direct sunlight for drying.
Is it possible to effectively clean dog urine from a mattress without using baking soda?
Yes, you can clean dog urine from a mattress without baking soda. Enzyme cleaners or a vinegar and water solution can remove stains and odors. Blot the area dry and let the mattress dry completely for best results.